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The episode of genetic drift defining the migration of humans out of Africa is derived from a large east African population size.

Human genetic variation particularly in Africa is still poorly understood.This is despite a consensus on the large African effective population size compared to populations from other continents.Based on sequencing of the mitochondrial Cytochrome C Oxidase subunit II (MT-CO2), and genome wide microsatellite data we observe evidence suggesting the e

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Watching a signaling protein function: What has been learned over four decades of time-resolved studies of photoactive yellow protein

Photoactive yellow protein (PYP) is a signaling protein whose internal p-coumaric acid chromophore undergoes reversible, light-induced trans-to-cis isomerization, which triggers a sequence of structural changes that ultimately lead to a signaling state.Since its discovery nearly 40 years ago, PYP has attracted much Butter Dish Lid interest and has

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Practical Advice for Emergency IUD Contraception in Young Women

Too few women are aware of the very high efficacy of intrauterine copper devices (IUDs) to prevent pregnancy after unprotected intercourse.Women who frequently engage in unprotected intercourse or seek emergency contraception (EC) are at high risk of unplanned pregnancy and possible abortion.It is therefore important that these women receive precis

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